Hints from the Health Department. Leaflet from the archive of the Society of Medical Officers of Health. Credit: Wellcome Collection, London
[Report of the Medical Officer of Health for London, City of ]
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No. of Sample. | Date of inoculation of Guinea Pig. | Dirt. | Date of Death. | Post Mortem Findings. | Result qua Tubercle. |
---|---|---|---|---|---|
14 | 16th March | Trace | 3rd May | Normal | Negative. |
15 | 16th March | Trace | 3rd May | Normal | Negative. |
16 | 16th March | Trace | 3rd May | Normal | Negative. |
17 | 16th March | Trace | 3rd May | Normal | Negative. |
18 | 16th March | Trace | 3rd May | Normal | Negative. |
19 | 22nd March | Trace | 5th April | Miliary nodules in spleen and liver. Caseous right inguinal glands. No tubercle bacilli found. Culture grows gram negative bacilli. Pus from gland inoculated into another guinea-pig. (See 19a.) | |
19a | 13th April | Nil | 16th June | Normal | Frustrate. |
20 | 22nd March | Trace | 4th May | Normal | Negative. |
21 | 22nd March | Trace | 4th May | Normal | Negative. |
22 | 22nd March | Nil | 4th May | Normal | Negative. |
23 | 22nd March | Trace | 4th May | Small caseous glands in right inguinal and lumbar regions. Tuberculosis of spleen. Early tuberculosis of liver. Tubercle bacilli demonstrated in spleen. | Positive. |
24 | 22nd March | Trace | 4th May | Normal | Negative. |
25 | 7th Oct. | Nil | 22nd Nov. | Tuberculous glands in right inguinal region. Early tuberculosis of spleen and liver. Tubercle bacilli demonstrated in spleen. | Positive. |
26 | 7th Oct. | Nil | 22nd Nov. | Normal | Negative. |
27 | 7th Oct. | Nil | 22nd Nov. | Normal | Negative. |
28 | 7th Oct. | Trace | 22nd Nov. | Normal | Negative. |
29 | 7th Oct. | Nil | 22nd Nov. | Normal | Negative. |
30 | 7th Oct. | Nil | 22nd Nov. | Normal | Negative. |
31 | 10th Oct. | Nil | 27 th Nov. | Normal | Negative. |
32 | 10th Oct. | Trace | 27th Nov. | Normal | Negative. |
33 | 10th Oct. | Trace | 27th Nov. | Normal | Negative. |
34 | 10th Oct. | Nil | 27th Nov. | Normal | Negative. |
35 | 10th Oct. | Nil | 27th Nov. | Normal | Negative. |
36 | 10th Oct. | Nil | 27th Nov. | Normal | Negative. |
37 | 10th Oct. | Nil | 1st Dec. | Normal | Negative. |
38 | 12 th Oct. | Trace | 1st Dec. | Normal | Negative. |
39 | 12th Oct. | Nil | 1st Dec. | Normal | Negative. |
40 | 12th Oct. | Nil | 1st Dec. | Normal | Negative. |
41 | 12th Oct. | Nil | 1st Dec. | Normal | Negative. |
42 | 12 th Oct. | Nil | 1st Feb. | Tuberculous glands in right inguinal and lumbar regions. Early tuberculosis of liver and advanced tuberculosis of spleen. Tubercle bacilli demonstrated in inguinal glands. | Positive. |
43 | 17th Oct. | Trace | 6th Dec. | Large abscess in right inguinal region, containing coliform bacilli and streptococci. No other lesions. | Negative. |
44 | 17th Oct. | Nil | 6th Dec. | Normal | Negative. |
45 | 17th Oct. | Trace | 6th Dec. | Normal | Negative. |
46 | 17th Oct. | Nil | 30th Oct. | Normal | Frustrate. |
47 | 17th Oct. | Nil | 6th Dec. | Normal | Negative. |
48 | 17th Oct. | Nil | 27th Nov. | Normal | Negative. |
49 | 8th Nov. | Nil | 19th Dec. | Normal | Negative. |
50 | 8th Nov. | Nil | 19th Dec. | Normal | Negative. |
"Dirt.— As regards dirt, about half the samples were clean, and half contained a trace, but none
could be considered objectionable.
"Tuberculosis.— Two samples (Nos. 8 and 11) were repetitions of samples found positive in
September last (viz., Nos. 2 and 43, 1932, respectively). In the first, the animal died within one week
of inoculation, and the experiment was therefore frustrate, and the second was again found to be
positive. As these samples were collected with bias, they have been excluded from the calculations.
"Three other animals died within one month, and have also been excluded. One of these (No. 19)
died 14 days after inoculation, and was found to have extensive disease of the internal organs. The
condition did not resemble tuberculosis, no tubercle bacilli could be demonstrated, and a second animal
inoculated with pus from a lymphatic gland, failed to develop tuberculosis in six weeks.
"Forty-four samples have, therefore, to be considered, and of these, five were found to contain
living tubercle bacilli, namely, 11.1 per cent."
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