London's Pulse: Medical Officer of Health reports 1848-1972

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London County Council 1897

[Report of the Medical Officer of Health for London County Council]

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6
The fact therefore remains that there has been in recent years relative increase of incidence of
diphtheria mortality upon the ages 3—, 4— and 5— which is not explicable on the hypothesis of
transference from scarlet fever.
2. Changes due to natural behaviour of the disease.—I have already shown in my annual report
for the year 1896 that there is reason for thinking that there are seasonal variations in the age
distribution of scarlet fever and diphtheria. The following tables (VI. and VII.), showing the results
obtained from the notification statistics of the years 1892—(5 I now reproduce.

TABLE VI. Diphtheria, 1892-6.

Month." All ages " taken as 1,000.
All ages.0—1—2—3—4—Under 5.5—10—15—20 and upwards.
January1,0002772901069539028910661154
February1,00029729110310139629210353156
March1,00027768510611040429210751146
April1,00031718510610840128710059153
May1,0002571841029637828311666157
June1,0001864819710136128711567170
July1,000245670949634028712773173
August1,000266083988435123812185205
September1,000205367919432529512380177
October1,000245873859433429412267183
November1,0002363791009736229410766171
December1,0002465871099538030011156153

TABLE VII. Scarlet Fever—Notifications, 1892-6.

Month." All ages " taken as 1,000.
All ages.0—1—2—3—4—Under 5.5—10—15—20 and upwards.
January1,00017416990953123911705770
February1,000144164821043053881716076
March1,00015417091943113761766572
April1,00017416585953033781786378
May1,00015407087913033761846374
June1,00016386588922994001716367
July1,00015356385942923921876267
August1,00017457589923183641787070
September1,00016345987912874191845555
October1,00016356585892904101825761
November1,00019376386922973941816365
December1,00017396592973103861745674

Examination of these tables, especially of the column "under 5," shows that, both in the case
of diphtheria and scarlet fever, children at the younger ages are attacked in relatively larger proportions
at the earlier and later parts of the year, and in less proportions in the summer months. There
is, indeed, in both diseases, indication of a curve of seasonal age variation. I have also shown that
the London cases of and deaths from scarlet fever and diphtheria indicate seasonal variations of fatality,
and in view of these circumstances it is impossible to affirm that the natural age incidence of diphtheria
mortality is always constant over a series of years. It is, however, obvious from the age distribution
of notified cases in August as compared with other months that there is another and important factor
concerned in determining the age incidence of diphtheria mortality.
Changes due to some social differences in the community.—This may be best considered by study
of other diseases of the same class as diphtheria. For this purpose the following tables* VIII., IX.
and X. have been prepared.
* The death rate at "all ages " is considerably influenced by variations in the age constitution of the population.

Suppose that a certain community in 1871 numbered 100,000 distributed in the following age groups, and that the deaths and corresponding death rates from whooping cough were as under—

All ages0—5.5—20.20—40.40 and upward*.
1871Population100,00010,00040,00030,00020,000
Whooping cough deaths2452004032
Whooping cough death-rate per 1,0002.45
2010.10.1
Death-rate at "All ages"
taken as 1001008164144