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Number of children of school age immunised
completed 419
Number of children of pre-school age immunised
completed 185
(i.e., 1935 cases only.)
Five hundred and ninety-eight children had Alum Precipitated
Toxoid, the remainder having Toxoid Antitoxin
Floccules.
The names and addresses of all children leaving the area
before completion of immunisation were reported forward to
the Medical Officers of Health of the respective areas.
Included in the total number of persons immunised with
Alum Precipitated Toxoid were eight children aged 1 to 5
years who were given 0.1 c.c. A.P.T. on two occasions at
approximately four weeks' interval. Posterior Schick tests
were done four weeks after the last injection, and all were
negative.
Twenty persons who had either been immunised or
naturally Schick negative in previous years were re-tested
during 1935, with the result that ten persons immunised
between 1932 and 1934 were still immune, and of the ten
naturally Schick negative in previous years, seven had become
Schick positive, showing a loss of natural immunity.
Of the cases immunised with Alum Preciptated Toxoid,
and excluding three who have not attended for posterior
Schick test, eight showed pseudo reactions three months
after injection of prophylactic. There was no case of a
definite failure to obtain a negative posterior Schick test.
During 1936, however, there have been frequent failures
to obtain a negative posterior Schick test after one dose of
A.P.T. Out of a total of 495 cases, 88.1 per cent, were negative.
The remainder have been given a further dose of 0.2
to 0.4 c.c. A.P.T. and up to the present there has been no
failure.
Present experience suggests that the method of choice
is to give 0.1 c.c. A.P.T. as a "detector" dose, followed by
0.2 to 0.4 c.c. two or three weeks later. One dose of A.P.T.
cannot be relied upon to produce immunity and the posterior
Schick test should not be omitted.
In nineteen persons immunised with A.P.T. over one
year previously, repeat posterior Schick tests were done and