London's Pulse: Medical Officer of Health reports 1848-1972

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City of London 1929

[Report of the Medical Officer of Health for London, City of ]

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No. ofSampleDate of inoculation ot DIRT. guinea pig.Date of Death.P.M. findings.Result qua tubercle.
25Traces Sept. 27Dead Oct. 20No sign of tubercle anywhere. Cause of death uncertain.Negative.
20„ „Killed Nov. 7Small quiescent abscess at site of inoculation. No T.B. found. Glands normal. B. Aer-trycke abscesses in spleen.„
27„ „No sign of tubercle anywhere„
28„ „Killed Nov. 14„ „„
29Clean „Dead Nov. 1„ „„
30Traces „Killed Nov. 14Early caseous regional glands—a few tubercle in spleen. T.B. microscopically and by culture.POSITIVE.
31Clean Oct. 1Killed Nov. 21NormalNegative.
32Mode-,,„,,,,
rately dirty.„„ „„
33Traces „„„„
34„ „„.„„
35Clean „Killed Nov. 25,,„
36Traces „Dead Oct. 6No sign of tubercle anywhere. B. Aertrycke abscesses in spleen.Experiment frustrate.
37Clean Oct. 8Killed Nov. 25NormalNegative.
38„ „„„„„„
39„ „Killed Nov. 28No sign of tubercle anywhere. B. Aertrycke abscess in one testis.„
40Traces „Killed Nov. 25Normal„
41Clean „Killed Nov. 28,,„
42Traces „Dead Nov. 19No sign of tubercle anywhere. Cause of death doubtful.„
43Clean Oct. 11Killed Nov. 28Normal„
44„ „,,„ .... .... .... .... ....„
45Traces „Killed Dec. 2,, .... .... .... .... ....,,
46 47„„„Local caseous abscess. Advanced tuberculous glands. Tubercle in spleen, liver and lung. T.B. abundant microscopically and by culture. NormalPOSITIVE. Negative.
48„Died Nov. 3No sign of tubercle anywhere. B. Aertrycke abscesses in spleen.„

Summary.—As regards dirt, 23 out of 48 samples could be classed as clean.
24 out of 48 samples contained small traces of dirt—i.e., a number
of small blackish specks in the deposit.
1 out of 48 samples was dirty, but only moderately so.
As regards tubercle: for one reason or another a number of the guinea pigs died
prematurely, the chief cause being an epidemic of B.
Aertrycke infection in the animal house. In 9 out of the
48 guinea pigs this premature death occurred so soon after
inoculation as to prevent any conclusion from the experiment.
But if the animal had lived 12 to 14 days or more
after inoculation, and no evidence of tubercle was to be
found, this has been returned as a negative result.
On this basis only 2 out of 39 milks showed the presence
of tubercle, or 5.1 per cent.
St. Bartholomew's Hospital, (Signed) F. W. ANDREWES.
January 6th, 1930.
The details in connection with the two samples in which the tubercle bacilli was present
were forwarded to the appropriate Medical Officers of Health, and the following are extracts
from the reports which have been received, and indicate the presence of tuberculous cattle
on the farms:—
Sample No. 30.—" An investigation was carried out at this farm on the 21st November,
1929, by the Acting County Medical Officer of Health.
"The herd consisted of forty-six cows. Two special samples were taken. One cow
was tuberculin-tested, but no milk was taken from it. The result of the examination of the
milk by animal inoculation was negative. Both mixed samples and both special samples
showed no tubercle bacilli. The cow which was tuberculin-tested reacted positively and
was slaughtered."
The Pathologist's findings were as follows:—
"There were very numerous lesions in lung tissue and substance of liver and also several
lesions on the peritoneum. In addition, the bronchial mediastinal hepatic and several
mesenteric lymphatic glands were affected. However, according to the wording of the
Order it must be shown as ' not advanced.'"
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