London's Pulse: Medical Officer of Health reports 1848-1972

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City of London 1914

[Report of the Medical Officer of Health for London, City of ]

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No. of Sample.Presence of dirt.Date of inoculation of guinea-pig.Date of animal's death.Condition found after death.Result as regards presence of tubercle bacilli.
21CleanOct. 28Killed Dec. 3Abscess at seat of inoculation, with tubercle bacilli in pus. Local and general glandular infection. Early tubercle in liver and spleen.Positive.
22Clean„Killed Dec. 4NormalNegative.
23Clean„Killed Dec. 4Local residual abscess, with a few cocci in pus, but no tubercle bacilli. Local lymph glands unaffected. Viscera normal.Negative.
24Clean„Died Nov. 5Dead in 8 days of spreading gangrene, starting from point of inoculation. In the cheesy remains of the injected material, a few acidfast bacilli were found, resembling tubercle bacilli. A further sample of this milk was taken (No. 49), but proved negative.Doubtfully positive.
25CleanOct. 30Killed Dec. 7NormalNegative.
26Clean„Killed Dec. 7Normal at seat of inoculation. Some tiny white specks in lung, liver and spleen. No tubercle bacilli found in them.Negative.
27Clean„Killed Dec. 7NormalNegative.
28Clean„Killed Dec. 8NormalNegative.
29Moderate amount of dirt.„Killed Dec. 8Small residual local abscess at seat of inoculation. No tubercle bacilli found in pus. Lymph glands and viscera normal.Negative.
30Clean„Killed Dec. 8Local abscess at point of inoculation, with tubercle bacilli in pus. Local lymph glands large and caseous. Liver and spleen full of tubercles.Positive.
31CleanNov. 4Died Nov. 24Died in 20 days, wasted, local abscess at point of inoculation, but no tubercle bacilli in pus. Lymph glands and viscera normal.Negative.
32Clean„Killed Dec. 9NormalNegative.
33Clean„Killed Dec. 9NormalNegative.
34Clean„Killed Dec. 10Small tuberculous abscess at seat of inoculation. Tubercle bacilli found. Lymph glands caseous. Early tubercles in liver and spleen.Positive.
35Clean„Killed Dec. 10NormalNegative.
36Clean„Killed Dec. 10NormalNegative.
37CleanNov. 5Killed Dec. 14Local tuberculous abscess at seat of inoculation. Tubercle bacilli found. Lymph glands caseous. Early tubercles in liver and spleen.Positive.
38Clean„Killed Dec. 14NormalNegative.
39Clean„Killed Dec. 14NormalNegative.
40Clean„Killed Dec. 15NormalNegative.
41Clean„Killed Dec. 15NormalNegative.
42Clean„Killed Dec. 15NormalNegative.
43CleanNov. 11Killed Dec. 16NormalNegative.
44Clean„Killed Dec. 16NormalNegative.
45Clean„Killed Dec. 16NormalNegative.
46Clean„Killed Dec. 17NormalNegative.
47Clean„Killed Dec. 17NormalNegative.
48Clean„Killed Dec. 17Residual abscess at seat of inoculation. No tubercle bacilli found in pus. Glands and viscera normal. Animal well nourished. (Duplicate of No. 21.)Negative.
49CleanNov. 18Killed Dec. 22NormalNegative.