Hints from the Health Department. Leaflet from the archive of the Society of Medical Officers of Health. Credit: Wellcome Collection, London
[Report of the Medical Officer of Health for London, City of ]
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No. of Sample. | Presence of dirt. | Date of inoculation of guinea-pig. | Date of animal's death. | Condition found after death. | Result as regards presence of tubercle bacilli. |
---|---|---|---|---|---|
21 | Clean | Oct. 28 | Killed Dec. 3 | Abscess at seat of inoculation, with tubercle bacilli in pus. Local and general glandular infection. Early tubercle in liver and spleen. | Positive. |
22 | Clean | „ | Killed Dec. 4 | Normal | Negative. |
23 | Clean | Killed Dec. 4 | Local residual abscess, with a few cocci in pus, but no tubercle bacilli. Local lymph glands unaffected. Viscera normal. | Negative. | |
24 | Clean | Died Nov. 5 | Dead in 8 days of spreading gangrene, starting from point of inoculation. In the cheesy remains of the injected material, a few acidfast bacilli were found, resembling tubercle bacilli. A further sample of this milk was taken (No. 49), but proved negative. | Doubtfully positive. | |
25 | Clean | Oct. 30 | Killed Dec. 7 | Normal | Negative. |
26 | Clean | „ | Killed Dec. 7 | Normal at seat of inoculation. Some tiny white specks in lung, liver and spleen. No tubercle bacilli found in them. | Negative. |
27 | Clean | „ | Killed Dec. 7 | Normal | Negative. |
28 | Clean | „ | Killed Dec. 8 | Normal | Negative. |
29 | Moderate amount of dirt. | „ | Killed Dec. 8 | Small residual local abscess at seat of inoculation. No tubercle bacilli found in pus. Lymph glands and viscera normal. | Negative. |
30 | Clean | „ | Killed Dec. 8 | Local abscess at point of inoculation, with tubercle bacilli in pus. Local lymph glands large and caseous. Liver and spleen full of tubercles. | Positive. |
31 | Clean | Nov. 4 | Died Nov. 24 | Died in 20 days, wasted, local abscess at point of inoculation, but no tubercle bacilli in pus. Lymph glands and viscera normal. | Negative. |
32 | Clean | „ | Killed Dec. 9 | Normal | Negative. |
33 | Clean | „ | Killed Dec. 9 | Normal | Negative. |
34 | Clean | „ | Killed Dec. 10 | Small tuberculous abscess at seat of inoculation. Tubercle bacilli found. Lymph glands caseous. Early tubercles in liver and spleen. | Positive. |
35 | Clean | „ | Killed Dec. 10 | Normal | Negative. |
36 | Clean | „ | Killed Dec. 10 | Normal | Negative. |
37 | Clean | Nov. 5 | Killed Dec. 14 | Local tuberculous abscess at seat of inoculation. Tubercle bacilli found. Lymph glands caseous. Early tubercles in liver and spleen. | Positive. |
38 | Clean | „ | Killed Dec. 14 | Normal | Negative. |
39 | Clean | „ | Killed Dec. 14 | Normal | Negative. |
40 | Clean | „ | Killed Dec. 15 | Normal | Negative. |
41 | Clean | „ | Killed Dec. 15 | Normal | Negative. |
42 | Clean | „ | Killed Dec. 15 | Normal | Negative. |
43 | Clean | Nov. 11 | Killed Dec. 16 | Normal | Negative. |
44 | Clean | „ | Killed Dec. 16 | Normal | Negative. |
45 | Clean | „ | Killed Dec. 16 | Normal | Negative. |
46 | Clean | „ | Killed Dec. 17 | Normal | Negative. |
47 | Clean | „ | Killed Dec. 17 | Normal | Negative. |
48 | Clean | „ | Killed Dec. 17 | Residual abscess at seat of inoculation. No tubercle bacilli found in pus. Glands and viscera normal. Animal well nourished. (Duplicate of No. 21.) | Negative. |
49 | Clean | Nov. 18 | Killed Dec. 22 | Normal | Negative. |