London's Pulse: Medical Officer of Health reports 1848-1972

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Holborn 1928

[Report of the Medical Officer of Health for Holborn Borough]

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DIPHTHERIA IN CHILDREN SCHICK TESTED) and Treated with Immunising Injections.

InitialsAge in years at date of Schick TestSexType of HomeDate of Schick TestFirst In jectionFinal InjectionRetestResult of RetestDate of onset of DiphtheriaInterval between last injection and date of onset of diseaseConfirmation of diagnosis byCharacter of Attack
1. A.C.4- 4/12M.Artizan— moderately satisfactory ; house let in lodgings30/1/247/2/2420/2/24 (Third)none—-18/3/2513 monthsMetropolitan Asylums Board (n.e. Hospital)Very severe
2. G.L.6 5/12M.Higher Artizan— model dwellings4/4/2311/4/2325/4/23 (Third)none-29/5/2513 monthsMetropolitan Asylums Board (n.e. Hospital)Very mild
3. M.T.3 3/12F.Higher Artizan— model dwellings24/9/241/10/2415/10/24 (Third)none-5/4/2618 monthsMetropolitan Asylums Board (n.e. Hospital)Mild
4. L.P.6 8/12F.Higher Artizan— part of private house11/11/2617/11/201/12/26 (Third)none-23/12/2622 days*Metropolitan Asylums Board (N. W. Hospital)Severe
5. R.H.7M.Residential, separate private house28/9/27 •5/10/2719/10/27 (Third]none--21/10/272 days*Cuddington lsola tion HospitalMild
6. P.P.1 8/12F.Artizan— model dwellings5/9/2312/9/2326/9/23 (Third)none-26/10/274 yearsMetropolitan Asylums Board (N.E. Hospital)Mild
7. J.F.1 10/12F.Higher Artizan-model dwellings13/5/2520/5/251''/6/25 (Tliird)yesnegative 11/11/2519/2/282 9/12 yearsMetropolitan As}'lums Board (N.E. Hospital)Mild
8. V.C.3 5/12F.Poor, one room; house let in lodgings9/4/2430/4/2118/6/24 (Third)yesnegative 12/9/2421/2/283 8/12 yearsMetropolitan Asylums Board (N.E. Hospital)Mild attack of nasa diphtheri;
"These two cases occurred before the elapse of 9 months, the period laid down at Edinburglas required to secure this artificial immunisation.

The above table shows that only two of the children were retested after the last injection. It cannot be assumed that immunity
invariably follows the administration of three immunising injections, nor that immunity even when once established is invariably
permanent. Drs. Parish and Okell have shown that of 440 Schick positive children who were rendered Schick negative by
immunisation, 5 per cent were found to be positive when retested 1-7 years later.