London's Pulse: Medical Officer of Health reports 1848-1972

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Holborn 1927

[Report of the Medical Officer of Health for Holborn Borough]

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TABLE VI. Batches of Toxin Antitoxin and Toxoid Antitoxin and the Flocculatea Antitoxin Coin pared.

Designation of batch of immunising mixture.No. of persons inoculated and retested.No. of these persons found positive on retesting.
Toxin antitoxin mixtureB. 346592
B. 475283
B. 654281
B. 6717418
B. 671A21
B. 672A302
B. 617352
B. 6751
B. 6721
T oxoid antitoxin mixtureB. 1017334
B. 1090161
B. 103813
B. 10184310
B. 1129183
B. 99510
B. 114882
B. 1197229
B. 1198153
B. 1205173
B. 20603
B. 207931
B. 208115
B. 22301
B. 230941
B. 2320172
B. 252511
B. 33777
B. 337821
Flocculated antitoxin mixtureT.A.F.2110
Total55578

Retesting.
Betesting is unpopular with parents, and the need for it does not help to
increase their confidence in immunisation. Of 555 that have been retested 68
were found to be still Schick positive after three inoculations and ten after T.A.F.
The facts relating to these are given in Table V.
That considerable importance attaches to the retesting is shown by the fact
that our six cases of diphtheria among those treated occurred in children who were
given the routine three injections, but had not been retested.
Diphtheria in Children Treated with Immunising Injections.
Up to the end of the year 1927 six cases of diphtheria occurred in children who
had been found positive on Schick test and treated with three immunising
injections.
Diphtheria was also notified as having occurred in three other children who
had completed their course of inoculation, but the diagnosis in these cases was
eventually not confirmed. Two of these (brother and sister) were removed to
M.A.B. hospitals as suffering from diphtheria, but they were diagnosed as suffering
from rubella and "carrying" diphtheria bacilli but not as suffering from diphtheria.
Both these children had been found negative to the re-Schick test some time
pieviouslv. The third was removed to M.A.B. hospital as suffering from
E 2