London's Pulse: Medical Officer of Health reports 1848-1972

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Holborn 1926

Report for the year 1926 of the Medical Officer of Health

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TABLE VI.

Batches of Toxin Antitoxin and Toxoid Antitoxin Compared

Designation of batch of toxin antitoxin mixture or toxoid antitoxin mixture.No. of persons inoculated and retested.Xo. of these persons found positive on retesting.
Toxin antitoxin -mixtureB. 346592
B. 475283
B. 654281
B. 6717418
B. 671a21
B. 672a302
B. 617352
B. 6751-
B. 6721
Toxoid antitoxin -mixtureB. 1017334
B. 1090161
B. 103813
B. 10184310
B. 1129183
B 99510
B. 114882
B. 1197219
B. 1198143
B. 1205173
B. 20601_
B. 207922_
B. 20818-
Total47264

Reactions.
Oar experience is that the reaction after the injection of the toxin antitoxin and
toxoid antitoxin is in practically every case negligible. All we have to record is that
in one child considerable swelling of the whole of the arm occurred, but the next day,
when at the centre, she was running about and helping the other children eat their
cakes ; the swelling went down without any further result. Another, a boy of 10 years
of age, his mother informed me, suffered with vomiting after each of his three
inoculations and spent the next day in bed, but he and his mother stuck to it, and he
was subsequently proved to have been satisfactorily immunised. In another child, a
small, hard, slightly tender nodule developed above the extornal condyle, but the
tenderness only remained for a few days.
The use of toxoid antitoxin does away with the risk of fatality incurred by
using improperly made toxin antitoxin.
What of the Future ?
Most of the attendances are the result of repeated efforts of persuasion and
encouragement. Prejudice against inoculation is widespread; some of the most
stubborn opponents of inoculation admit that if T.A.T. could be given in tabloid form