London's Pulse: Medical Officer of Health reports 1848-1972

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Wandsworth 1929

[Report of the Medical Officer of Health for Wandsworth, Metropolitan Borough]

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Infective Diseases.
29
Diphtheria to be ill only one day, and it is probable that if he
had not been immunised the attack would have been a virulent
one.
Case No. 3—A girl of 7—Schick Test positive—received
three doses of Toxoid Anti-toxin mixture—developed
Diphtheria 5 months and 9 days after the last dose—
membrane present and virulent organisms on culture
—Re-Schick Test performed on same day as admitted
to hospital was positive—the attack was only a slight
one—has not attended for further re-test. (Off Register.)
This child developed the disease before immunity was
established, as shown by the positive re-test.
Case No. 4—A girl who at the age of 14 months
received three immunising doses without a primary
Schick Test—she was not brought for Re-Schick Test—
two years later she had a severe attack of Clinical
Diphtheria and received 48,000 units of Anti-toxin— a
Schick Test performed 4 days later was negative—she
recovered from the attack.
In the absence of a Re-Schick Test before the attack of
Diphtheria one can only assume that the three injections given
two years previously had not been successful in producing
immunity and that this was another case of delay in the production
of immunity. The negative Re-Schick Test obtained
after the attack of Diphtheria might well have been due to the
large dose of Anti-toxin given in the treatment of the illness.
Scarlet Fever.
899 cases of Scarlet Fever occurred, compared with 752
in 1928, 816 in 1927 and 633 in 1926.
Six cases died, compared with three and five respectively
for the two previous years, and the death-rate was .016 per
1,000, compared with .008 and .01. The case mortality was
.66 per cent.

TABLE XV.

NUMBER OF DOSES AND TIME REQUIRED TO PRODUCE IMMUNITY—AS SHOWN BY A NEGATIVE

RE-SCHICK TEST.

Number of Immunising Injections given.Period after last injection of First Series in which re-Test was Negative.Total
within 4 monthsbetweenTotal within 1 yearbetween
4 and 6 months6 and 9 months9 and 12 months12 and 18 months18 mths and 2 years2 years and 2£ years
Children Under 15.
First Series2 injections214-7-2-9
3 injections438264128368662715-908
4 injections5--16---6
Second Series4 injections-----2--2
5 injections-----12-3
6 injections---66188133
Total Under 154452651324388548271961
Adults Over 15.
First Series3 injections910412431-28
4 injections-1--1---1
Second Series6 injections------2-2
Total All Ages4542761364491051301992