London's Pulse: Medical Officer of Health reports 1848-1972

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West Ham 1937

[Report of the Medical Officer of Health for West Ham]

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the discharge from both ears dried up. He ultimately made a
complete recovery.
A trial was also made of the value of prontosil and proseptasine
for the prevention of the complications of scarlet fever when
administered early in the disease. The two drugs were used in
about an equal number of cases, and the dosage employed was
5 to 10 c.c.s of the soluble preparation injected intramuscularly on
admission, followed by the oral administration of one tablet three
times a day for four days. In 150 cases so treated no beneficial
effects were observed. There was no diminution of toxic symptoms
during the acute stage, and the incidence of complications was
not reduced when compared with non-treated cases. Four cases
developed a papular rash a fortnight after the administration of
the drug, but no other toxic effect was observed.
Of the 777 cases discharged, 264, or 33.98 per cent., suffered
from complications as shown in Table VI.

Table VI.

Scarlet fever. Frequency of complications.

Complication.No. of cases.Per cent. of all cases.
Adenitis648.23
Albuminuria172.18
Arthritis81.02
Nephritis50.64
Otorrhoea617.85
Rhinitis627.97
Septic sores182.32
Tonsillitis232.95
Vaginitis60.77
All complications26433.98

The average duration of residence of all cases was 38.47
days.
Return cases. The number of "return cases" of scarlet
fever which were admitted to this hospital during the year was 28.
When considered in relation to the 777 scarlet fever patients discharged
during the year, this number gives a return case rate of
3.60 per cent. The monthly incidence is shown in Table VII.
160