London's Pulse: Medical Officer of Health reports 1848-1972
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Hints from the Health Department. Leaflet from the archive of the Society of Medical Officers of Health. Credit: Wellcome Collection, London
Heston and Isleworth 1932
[Report of the Medical Officer of Health for Heston and Isleworth]
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An analysis of 2292 Schick positive cases who received 3 one c.c. injections of T.A.M. as the original immunising course and were retested from 4 to 7 months later.
| Age. | Neg. after 3 T.A.M. | Neg. only after additional injections. | Positive after 3 T.A.M. and not yet completed. | % not immunised by 3 injections. |
|---|---|---|---|---|
| 1 | 108 | 3 | 2 | 4.4 |
| 2 | 107 | 4 | 1 | 4.4 |
| 3 | 115 | 6 | 1 | 5.7 |
| 4 | 131 | 10 | 3 | 9.0 |
| 5 | 232 | 40 | 2 | 15.3 |
| 6 | 241 | 38 | 4 | 14.8 |
| 7 | 223 | 31 | 2 | 12.9 |
| 8 | 234 | 36 | 4 | 14.6 |
| 9 | 222 | 27 | 4 | 12.2 |
| 10 | 188 | 20 | 2 | 10.4 |
| 11 | 91 | 9 | 2 | 10.7 |
| 12 | 62 | 12 | 2 | 18.4 |
| 13 & over | 65 | 5 | 3 | 10.9 |
| Total | 2019 | 241 | 32 | 11.9% |
N.B.—Injections 1 and 2 of 1 c.c. of T.A.M. were given at weekly intervals. The third injection
of 1 c.c. was given 14 days after the seconds.
An analysis of 355 cases who were originally Schick positive and received an immunising course of 2 one c.c. injections of T.A.M. at weekly intervals and a third injection of 1.5 c.c.s of T.A.M. 14 days after the second injection. They were re-tested at various times over four months from the last immunising injection.
| Age. | Neg. after 3 injections. | Neg. only after additional injections. | Positive after 3 T.A.M. and not yet completed. | % not immunised by 3 injections. |
|---|---|---|---|---|
| 1 | 23 | 0 | 1 | 4.1 |
| 2 | 24 | 5 | 1 | 20.0 |
| 3 | 20 | 4 | 3 | 25.8 |
| 4 | 27 | 1 | 1 | 6.9 |
| 5 | 56 | 7 | 4 | 16.4 |
| 6 | 46 | 7 | 2 | 16.3 |
| 7 | 33 | 5 | 1 | 15.3 |
| 8 | 14 | 2 | 0 | 12.5 |
| 9 | 23 | 0 | 0 | 0.0 |
| 10 | 20 | 3 | 1 | 16.6 |
| 11 | 15 | 1 | 2 | 16.6 |
| 12 | 2 | 0 | 1 | 33.3 |
| 13 & over | 0 | 0 | 0 | |
| Total | 303 | 35 | 17 | 14.6 |
The present short series of 355 cases does not appear to show any advantage at all in using
a 3rd injection of 1.5 c.c. instead of 1 c.c. but this can probably only be determined after a much
longer experience.
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