London's Pulse: Medical Officer of Health reports 1848-1972

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Ilford 1959

[Report of the Medical Officer of Health for Ilford]

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139
Treatment Number of Cases
3. Bed buzzer 6 )
)
4. Phenobarbitone 3 )
) 50%
5. Charting 3 )
)
6. Disipidin Snuff 1 )
Although this is necessarily a limited survey,
both the treatment indicated and the results obtained
show an interesting preponderance ofenuretic children
with deep sleeping habits , over enuretic children
where other etiological factors are concerned.
The Use of "Dexten" (Dexamphetamine-resinate)
A number of these tablets was issued for use at
the IlfordEnuresis Clinic as it was felt that it would
be interesting to compare a series of cases treated
with this long acting substance, with a comparable
series treated with the short-acting, non-bonded
amphetamine salt. This work is still continuing, but
the number of cases treated is not yet sufficient to
enable a true comparison to be made. During previous
years, amphetamine sulphate (Benzedrine) has often
been given in divided doses, e.g. at 7p.m. and 11 p.m.
with encouraging results, so that the use of Dexten
in avoiding the necessity of waking a child for the
second dose is already obvious.
It has been shown that the rate of release of dexamphetamine
from Dexten (determined by in-vitro
experiments) is as follows:-
Time after ingestion % liberated
(hr s.)
2 hours 26
4 41
6 51
8 62
10 75
12 85
14 85
(Sir Adolphe Abrahams, The Lancet, December 28th
1957).