Hints from the Health Department. Leaflet from the archive of the Society of Medical Officers of Health. Credit: Wellcome Collection, London
[Report of the Medical Officer of Health for London County Council]
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but that injections with A.P.T. involved a smaller increase in risk, and one to which less
statistical confidence could be attached. In July to September the increase of risk for the
combined vaccine was five times and even for A.P.T. the risk may have been multiplied
three times. The action taken in discontinuing the use of the combined vaccine during
September, 1949, was, therefore, fully justified. It does not follow that these considerations
would apply in the face of any future epidemic as the newer combined prophylactics
may not be subject to the same risks and it is now the practice in many areas to
suspend inoculation during epidemic prevalence of poliomyelitis.
We are indebted to Dr. J. Knowelden, of the London School of Hygiene and
Tropical Medicine, for much helpful advice during the protracted course of the calculations
involved in this investigation.
References:
1.McCloskey, B.P. (1950), * Lancet', 1, 659.
2. Proc. of Royal Soc. Med. (1950) Vol. XLIII, No. 4.
3. Bradford Hill, A. and Knowelden, J., B.M.J. (1950) vol. ii, p. 1.
APPENDIX C STATISTICS
Table 1—
Year | Mid-year estimate of population | Average age | ||||||
---|---|---|---|---|---|---|---|---|
Total | 0-4 | 5-14 | 15-24 | 25-44 | 45-64 | 65+ | ||
1921 | 4,484,523 | 376,055 | 809,212 | 796,590 | 1,365,546 | 877,145 | 259,975 | 31.2 |
1926 | 4,605,400 | 404,800 | 746,900 | 826,300 | 1,380,400 | 961,300 | 285,700 | 31.9 |
1931 | 4,374,300 | 297,700 | 646,700 | 827,940 | 1,330,200 | 951,000 | 320,760 | 33.4 |
1936 | 4,141,100 | 254,400 | 576,600 | 729,500 | 1,306,100 | 935,700 | 338,800 | 34.5 |
1937 | 4,094,500 | 249,300 | 555,000 | 721,800 | 1,296,800 | 930,000 | 341,600 | 34.7 |
1938 | 4,062,800 | 249,300 | 538,600 | 709,700 | 1,291,200 | 927,300 | 346,700 | 34.8 |
1939 | 3,800,300 | 211,900 | 457,500 | 3,130,900 | ||||
1940 | 3,236,600 | 141,300 | 232,500 | 2,862,800 | ||||
1941 | 2,507,800 | 79,200 | 142,100 | 2,286,500 | ||||
1942 | 2,634,800 | 137,700 | 234,500 | 2,262,600 | ||||
1943 | 2,794,200 | 179,500 | 282,000 | 2,332,700 | ||||
1944 | 2,753,600 | 172,000 | 302,300 | 2,279,300 | ||||
1945 | 2,906,900 | 189,720 | 311,440 | 2,405,740 | ||||
1946 | 3,272,500 | 227,470 | 353,050 | 2,691,980 | ||||
1947 | 3,409,300 | 259,000 | 364,600 | 2,785,700 | ||||
1948 | 3,397,900 | 269,900 | 359,500 | 2,768,500 | ||||
1949 | 3,389,850 | 276,200 | 367,000 | 2,746,650 | ||||
1950 | 3,389,620 | 276,200 | 370,000 | 1,437,960 | 1,305,460 | |||
1951 | 3,358,000 | 274,000 | 381,000 | 419,000 | 1,101,000 | 812,000 | 371,000 | 36.9 |
1952 | 3,363,000 | 256,000 | 400,000 | 416,000 | 1,091,000 | 822,000 | 378,000 | 37.1 |