London's Pulse: Medical Officer of Health reports 1848-1972

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Wandsworth 1938

[Report of the Medical Officer of Health for Wandsworth, Metropolitan Borough]

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Infective Diseases. 31
XII, giving this information. The six cases referred to in the
previous paragraph are not included in the Table, which deals
with 6,290 persons.
It will be noticed that the time taken to produce immunity is
shown to vary very much. The period which elapses between
the last injection of the immunising dose and the re-Schick test
depends to a large extent on the date when the person concerned
attends at the Clinic to be re-tested. Some of it is due, however,
to actual delay in the production of immunity. A number
of the cases included in this Table because the final re-test was
negative have had one or more positive results before the final
negative one was obtained.
An analysis of the information given in Table XII. brings
out the following points:—
(1) One series of injections was sufficient to produce
immunity in most of the cases—actually 5,451 out of 6,290
were immunised after the first series.
(2) 771 cases required a second series of injections to
produce the same result.
(3) In a few cases further injections had to be given
before immunity was produced.
(4) 4,637 out of 6,290 cases were protected within six
months after receiving the last dose of immunising serum.
(5) By the end of twelve months this number had
increased to 5,773. There are good grounds for assuming that
a proportion of the remainder would have been found protected
if they had attended earlier to be re-tested.
In addition to the 6,290 persons who have been protected,
350 have completed the first series of injections but cannot be
recorded as protected because the last re-Schick test has given a
positive result. 100 of these have not attended since this positive
re-test. The other 250 have attended the Clinics and have
received further injections but have not yet reacted negative to
the re-Schick test.