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Immunology of infertility.
Hendry, W. F
The following summary accompanies the cassette: "Antisperm antibodies may occur in men or women as a result of exposure of the sperms to systemic immune cells. If the quantity of antisperm antibodies formed is sufficient then they can interfere with fertility. Men usually get much higher titres of antibodies than women, and it has been shown that high titres of antisperm antibodies are the primary cause of infertility in approximately 10% of sub-fertile men. The situation in women is far more complex, where low titres of antisperm antibodies are common and where false positive results make interpretation difficult. The different tests available to detect antisperm antibodies are described, and a method of checking the result of the test is defined. The essential difference between naturally infertile men and men following vasectomy is discussed and the probably nature of future research in immunological infertility is outlined."
Segment 1 Chamberlain introduces the lecture. Hendry discusses the differences between sperms and shows diagrams relating to antisperm antibodies. Time start: 00:00:00:00 Time end: 00:04:33:00 Length: 00:04:33:00 Segment 2 Hendry talks about antibody tests as part of an investigation to find the cause of infertility. He then discusses agglutination tests in men and women. Time start: 00:04:33:00 Time end: 00:10:27:00 Length: 00:05:54:00 Segment 3 Hendry discusses the results of various studies into infertile men and women. He shows an illustration depicting the effects of cervical mucous on sperm in the presence of antisperm antibodies. Time start: 00:10:27:00 Time end: 00:15:38:00 Length: 00:05:11:00 Segment 4 Hendry demonstrates the results of antisperm antibody tests following vasectomy. Chamberlain and Hendry, seated, discuss the subject of the lecture. Time start: 00:15:38:00 Time end: 00:20:39:00 Length: 00:05:01:00 Segment 5 Chamberlain and Hendry continue to discuss infertility. They also mention Hendry's book on infertility. Time start: 00:20:39:00 Time end: 00:25:48:19 Length: 00:05:09:19
Discussed by Mr Geoffrey Chamberlain and Mr WF Hendry, St Bartholomew's Hospital. Medical editor: Mr Geoffrey Chamberlain, Institute of Obstetrics and Gynaecology, London. Produced by Jennie Smith. Made by University of London Audio-Visual Centre. Made for British Postgraduate Medical Federation in association with the Blair Bell Research Society.
This video is one of around 310 titles, originally broadcast on Channel 7 of the ILEA closed-circuit television network, given to Wellcome Trust from the University of London Audio-Visual Centre shortly after it closed in the late 1980s. Although some of these programmes might now seem rather out-dated, they probably represent the largest and most diversified body of medical video produced in any British university at this time, and give a comprehensive and fascinating view of the state of medical and surgical research and practice in the 1970s and 1980s, thus constituting a contemporary medical-historical archive of great interest. The lectures mostly take place in a small and intimate studio setting and are often face-to-face. The lecturers use a wide variety of resources to illustrate their points, including film clips, slides, graphs, animated diagrams, charts and tables as well as 3-dimensional models and display boards with movable pieces. Some of the lecturers are telegenic while some are clearly less comfortable about being recorded; all are experts in their field and show great enthusiasm to share both the latest research and the historical context of their specialist areas.
Current Research in Obstetrics and Gynaecology