re: Identification of HMC [Correspondence]

Date:
1 July 1952 - 25 June 1953
Reference:
PP/GRW/B/4
Part of:
Wyatt, Gerard R. (1925-)
  • Archives and manuscripts
  • Online

Collection contents

Available online

view re: Identification of HMC [Correspondence]

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In copyright

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Credit

re: Identification of HMC [Correspondence]. In copyright. Source: Wellcome Collection.

About this work

Description

Dr. G. R Wyatt's correspondence regarding the identification of a component found in certain nucleic acids, Cx, as 5-hydroxymethylcytosine (HMC). This file holds letters sent to and from Dr J. M. Sprague, Dr. J Spizizen, Dr. B Hampil and Dr. C. S. Miller concerning the transfer and analysis of both nucleic acids isolated from viruses and of synthetically obtained HMC. Of particular note is a letter dated January 31st 1953 in which G. R.Wyatt wrote to Dr. Hampil. This letter contains results of a quantitative analysis of vaccinia nucleic acids which shows the molar quantities of adenine and thymine, and also guanine and cytosine to be near equal and thus these results are "in accordance with what seems to be a quite general (and quite unexplained!) rule in DNA's."

Publication/Creation

1 July 1952 - 25 June 1953

Physical description

1 file c.25 loose letters

Arrangement

Order as found

Related material

Within this collection: PP/GRW/A/6; PP/GRW/A/7; PP/GRW/B/1; PP/GRW/B/3; PP/GRW/B/6

Location of duplicates

A digitised copy is held by Wellcome Collection as part of Codebreakers: Makers of Modern Genetics.

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