Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)
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Immunology of infertility. Attribution-NonCommercial 4.0 International (CC BY-NC 4.0). Source: Wellcome Collection.
The following summary accompanies the cassette: "Antisperm antibodies may occur in men or women as a result of exposure of the sperms to systemic immune cells. If the quantity of antisperm antibodies formed is sufficient then they can interfere with fertility. Men usually get much higher titres of antibodies than women, and it has been shown that high titres of antisperm antibodies are the primary cause of infertility in approximately 10% of sub-fertile men. The situation in women is far more complex, where low titres of antisperm antibodies are common and where false positive results make interpretation difficult. The different tests available to detect antisperm antibodies are described, and a method of checking the result of the test is defined. The essential difference between naturally infertile men and men following vasectomy is discussed and the probably nature of future research in immunological infertility is outlined." 5 segments.